Millimeter Wave Therapy: A Comprehensive Analysis of Principles, Applications, and Scientific Evidence

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  • January 01, 2026
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  • Millimeter Wave Therapy: A Comprehensive Analysis of Principles, Applications, and Scientific Evidence

1. What are Millimeter Waves?

Millimeter waves refer to electromagnetic waves with wavelengths between 1–10 mm, corresponding to a frequency range of 30 GHz–300 GHz, belonging to the extremely high-frequency (EHF) band. They possess the following characteristics:

  • Low Power, Non-Thermal Effect: Treatment does not generate significant heat and does not damage tissues.

  • Shallow Penetration: Energy is primarily absorbed by the superficial layers of the skin, reaching a depth of about 300 micrometers.

  • Non-Ionizing Radiation: Does not break chemical bonds, classified as non-ionizing radiation, with relatively high safety.


2. Mechanisms of Action of Millimeter Wave Therapy

2.1 Biological Resonance Theory

Macromolecules in human tissues (such as cell membranes, proteins, DNA, etc.) have their own natural vibration frequencies. Disorders in these frequencies may lead to diseases. The frequency of millimeter waves is close to the natural frequency of human tissues. Through resonance effects, they can help cells restore normal physiological states.

2.2 Non-Thermal Effects and Distal Effects

  • Non-Thermal Effects: Treatment does not rely on heating but directly influences cellular functions through electromagnetic fields.

  • Distal Effects: Energy can be transmitted to distant lesion sites through meridians, nerves, body fluids, and other pathways, achieving systemic regulation.

2.3 Immunomodulation and Repair Functions

Multiple studies indicate that millimeter waves can:

  • Enhance the activity of T cells and NK cells

  • Promote the phagocytic function of macrophages

  • Regulate immune balance and reduce the side effects of chemotherapy

  • Promote tissue repair and inflammation absorption


3. Main Clinical Applications and Scientific Evidence

Pain Management

  • Research Support: Multiple randomized controlled trials show that millimeter waves can relieve headaches, arthritis, postoperative pain, and neuropathic pain.

  • Mechanism: Likely involves activating the endogenous opioid system and inhibiting pain signal transmission.

Diabetic Complications

  • Diabetic Peripheral Neuropathy: A study involving 51 patients showed that millimeter wave treatment significantly improved the Toronto Clinical Neuropathy Score (TCNS).

  • Diabetic Foot and Ulcers: Promotes microcirculation and accelerates ulcer healing.

Adjuvant Cancer Therapy

  • Immune Protection: Millimeter waves can mitigate chemotherapy-induced immunosuppression, enhancing the activity of T cells and NK cells.

  • Inhibition of Metastasis: Animal experiments show that combining millimeter waves with chemotherapy can reduce lung metastasis rates in melanoma.

Inflammation and Repair

  • Suitable for osteoarthritis, rheumatoid arthritis, soft tissue injuries, etc., with anti-inflammatory, swelling-reducing, and repair-promoting effects.


4. Treatment Methods and Precautions

Selection of Treatment Sites:

  • Commonly used sites include acupuncture points, lesion projection areas, or pain points.

  • For example: For diabetes, irradiation can be applied to the pancreatic projection area, Zusanli (ST36), Shenshu (BL23), and other acupuncture points.

Treatment Parameters:

  • Commonly used frequencies: 30–70 GHz

  • Power density typically ranges from 1–10 mW/cm²

  • Each session lasts 20–30 minutes, once daily

Contraindications:

  • Patients with eye diseases

  • Individuals with cardiac pacemakers

  • Pregnant women or patients with bleeding disorders


5. Device Types and Home-Use Trends

Home-use millimeter wave therapy devices are now available on the market, such as the "HWB-111" model. These devices are user-friendly and suitable for home self-care. They typically include a host unit, irradiation head, straps, and feature functions like timers and power adjustment.


6. Conclusion: A Scientific Perspective on Millimeter Wave Therapy

Millimeter wave therapy, as an adjuvant, non-pharmacological, non-invasive treatment method, shows potential in pain management, diabetic complications, and adjuvant cancer therapy. Its mechanisms involve immunomodulation, neural regulation, and cellular repair, among other aspects.

However, most current studies are still based on small sample sizes. More high-quality, large-sample randomized controlled trials are urgently needed to verify its long-term efficacy and safety. Patients are advised to use such devices under the guidance of a physician and not to replace mainstream medical treatments.


References (Partial):

  • Usichenko T.I. et al. (2006). Low-Intensity Electromagnetic Millimeter Waves for Pain Therapy. eCAM.

  • Logani M.K. et al. (2011). Millimeter Wave and Drug Induced Modulation of the Immune System. J Cell Sci Ther.

  • Moazezi Z. et al. (2008). Low Intensity Millimeter Wave as a Potential Tool in Treatment of Diabetic Sensorymotor Polyneuropathy.


If you are interested in millimeter wave therapy, it is recommended to consult a professional doctor or therapist to develop a reasonable usage plan based on your individual circumstances. On the path to health, science and caution go hand in hand.

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